Rockefeller University Research Assistant | Laboratory of Molecular Biology in New York, New York
Research in the Laboratory of Molecular Biology, led by Dr. Nathaniel Heintz, aims to identify the genes, circuits, cells, macromolecular assemblies, and individual molecules that contribute to the function of the mammalian brain and to its dysfunction in disease. Understanding the distinct classes of neurons and the circuits that control specific aspects of cognition and behavior can lead to more targeted treatments for central nervous system disorders.
The goal of this project is to identify novel strategies to delay onset and/or slow progression of Huntingdon's disease.The Research Assistant will be responsible for the preparation of human brain samples for next generation sequencing.
Specific tasks include:
Isolation of cell components with antibodies or DNA probes (via FACs)
PCR, gel electrophoresis and library preparation
Preparing genetic material for trinucleotide repeat sizing
Good computer skills and familiarity with NCBI database tools.
Good communication skills
Ablity to keep clear accurate records
Previous experience with RNA isolation and in situ hybridization
Familiarity with established profiling assays such as ATAC-Seq, bisulfite-Seq and Ox-bisulfite-Seq to elucidate the epigenetic properties of the DNA
Rockefeller University does not discriminate in employment on the basis of race, color, religion, sex (including pregnancy, gender identity), national origin, political affiliation, sexual orientation, marital status, disability, genetic information, age, membership in an employee organization, retaliation, parental status, military service or other non-merit factor. All qualified applicants will receive consideration for employment without regard to the characteristics listed above.
Compensation Range: Min
Compensation Range: Max
Job Locations US-NY-New York
Position Type Regular Full-Time