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Rockefeller University Research Assistant | Laboratory of Molecular Biophysics in New York, New York

Organization Overview

All cells make RNA with a complex molecular machine, the DNA-dependent RNA polymerase. The Laboratory of Molecular Biophysics, led by Dr. Seth A. Darst and Dr. Elizabeth A. Campbell, determines three-dimensional structures of RNA polymerase and associated proteins as it progresses through the transcription cycle. We study the model system Escherichia coli to understand fundamental mechanisms and regulation of the transcription cycle, and we study bacterial pathogens such as Mycobacterium tuberculosis to diversify our understanding and to provide a basis for therapeutic development. The structure and function of the SARS-CoV-2 RNA synthesis machinery is also under study.


The Research Assistant will execute scientific experiments under the guidance of senior scientists as well as help maintain laboratory functions such as making general solutions or calibrating equipment.


Responsibilities include:

  • Conducting experiments that involve cloning, expressing and purifying proteins

  • Purifying RNA/DNA

  • Running radioactive based transcription assays

  • Pickup packages/minor lab maintenance


Bachelor's degree required, with a 2-year commitment. Basic chemistry, microbiology lab techniques and experience in cloning is a plus. Must be adept at using general lab equipment such as centrifuges, pH meters, pipettes, gel electrophoresis. Preferred but not required: experience in over expressing and purifying proteins.

Rockefeller University does not discriminate in employment on the basis of race, color, religion, sex (including pregnancy, gender identity), national origin, political affiliation, sexual orientation, marital status, disability, genetic information, age, membership in an employee organization, retaliation, parental status, military service or other non-merit factor. All qualified applicants will receive consideration for employment without regard to the characteristics listed above.

Compensation Range: Min

USD $46,000.00/Yr.

Compensation Range: Max

USD $50,000.00/Yr.

Job Locations US-NY-New York

Category Science

Position Type Regular Full-Time